The San Francisco 49ers certainly have had some bad luck so far this season and are dealing with some high-profile injuries.

Injuries already are accruing across the NFL, knocking several star players out and forcing teams to turn to backups and ...

The San Francisco 49ers placed running back Christian McCaffrey on injured reserve on Aug. 14 but have yet to fill his vacant ...

George Kittle missed practice on Thursday because of a hamstring injury. Here's the latest on the TE's status for the Week 3 ...

Herbert injured his right leg in the third quarter of Week 2’s 26-3 win against the Carolina Panthers trying to escape the ...

Purdy still hasn't entirely shaken the "system" quarterback label and other denigrations. A chance for his rebuttal is now ...

Week 3 matchup vs. Rams with key injuries to McCaffrey, Samuel, and Kittle, testing their depth in this crucial NFC West ...

Injuries have caused many problems for the San Francisco 49ers this year, and now Brock Purdy has lost another offensive ...

Defensive coordinator Nick Sorensen and run game coordinator and offensive line coach Chris Foerster reviewed the 49ers ...