Demi Moore stars in the film about an aging actress who takes a black market drug to create a younger version of herself.

The first big update to U.S. methadone regulations in 20 years is poised to expand access to the life-saving drug starting ...

Warning: This article contains spoilers for The Substance."Yeah, I'd do it too," I thought of "the substance", as I sat in ...

Workers at the state board have begun wearing gloves when handling mail and are taking additional precautions.

Officers from the Ridgecrest Police Department conducted a traffic stop in the 700 block of W. Inyokern Rd. that led to the ...

A former FBI agent commented following a suspicious letter containing white powder addressed to Lt. Gov. Deidre Henderson’s ...

“The Substance” was lauded upon its premiere at the Cannes Film Festival earlier this year, where it was up for the Palme ...

The FBI investigates a white powder-containing letter sent to Utah’s Lt. Gov. Deidre Henderson, prompting safety concerns.

Kratom may be new to you, but state officials and federal regulators are already very familiar with the herbal product.

Demi Moore, Margaret Qualley, and filmmaker Coralie Fargeat break down the bloody ending of "The Substance." Warning: This ...

The Substance, Coralie Fargeat’s outrageous new body-horror movie, ends the only way it can: in a great, explosive bloodbath.